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Clinical Application

Alpha-thalassemia (α-thalassemia) is a kind of monogenic inheritance hemopathy due to expression imbalance of peptide chain caused by alpha -globin gene mutation of locus 16p13.3 of No. 16 chromosome. The common alpha -globin gene mutation types are three deletion types of -- ^SEA, -α ^3.7 and -α ^4.2 and three non-deletion types of α^CSα, α^QSα and α^WSα.

Intended Use

This kit is used for the qualitative detection of human whole blood genomic DNA sample, which can detect the 3 common sorts of non-deletion type alpha-thalassemia gene mutation (α^Tthalassemia): α^{Constant Springα} (α^CSα), α^{Quong Sze}α (α^QSα) and α^Westmeadα (α^WSα).

General Specification

Methodology: PCR-Reverse Dot Blot
Sample Type: anti-coagulation whole blood
Precision: CV <5%
LoD: 10 ng/&mu;L

Packing Specifications

Demonstration of Results